8号染色体计数探针

8号染色体计数探针

 广州健仑生物科技​有限公司 

本司长期供应尼古丁（可替宁）检测试剂盒，其主要品牌包括美国NovaBios、广州健仑、广州创仑等进口产品，国产产品，试剂盒的实验方法是胶体金方法。

我司还有很多荧光原位杂交系列检测试剂盒以及各种FISH基因探针和染色体探针等，。

8号染色体计数探针

   本试剂盒主要用于8号染色体计数的检测，里面包括即用型杂交液和DAPI复染剂。
本试剂盒仅供科研使用。

欢迎咨询

欢迎咨询

以下是我司出售的部分FISH产品：

二维码扫一扫

【公司名称】 广州健仑生物科技有限公司
【】    杨永汉 

【】
【腾讯 】
【公司地址】 广州清华科技园创新基地番禺石楼镇创启路63号二期2幢101-3室

【企业文化宣传】

在刑侦领域，死亡时间的确定是破案zui重要的线索之一，围绕它展开的相关研究一直没有停止。但是，现实没有我们想得那么乐观。专家表示，现在业内还是用传统方法居多，而以基因表达确定死亡时间，尽管法医专家已经研究了很多年，但仍停留在实验室，离真正应用还有较长的路要走。

一直没有*方法

到目前为止，法医学领域推断死亡时间的技术手段，主要是依据尸体现象，如尸僵、尸斑、尸温等，胃内容的消化程度以及尸体周围、植物的生长变化规律等。“准确推断死亡时间是法医学界*的难题，目前尚未有不受个体差异和死后变化影响的‘金指标’可用于实际案件。”gongan部物证鉴定中心法医病理损伤技术处副处长何光龙说。

从专业的角度讲，根据尸体现象推断死亡时间的方法多与统计学有关，也有相关的公式。但正如何光龙所说，环境的温湿度、死者的体格、死亡原因等各种因素都会造成死后变化的个体差异性，从而影响死亡时间推断的准确性。比如，通过尸温变化来推断早期死亡时间在目前案件中应用较广，但尸温的变化受死者的胖瘦、衣着状态、周围环境的温度变化等多因素干扰。相同环境下胖子的尸温比瘦子的尸温降低得慢；温暖室内的尸温比寒冷室外的尸温冷得要慢。因此，现在法医学对死亡时间的鉴定是一个相对粗略的时间区间段判断。

“基因表达法”为什么目前不靠谱

大概从十几年前开始，中国法医学界开始探讨是否可以通过监测人死后基因表达的变化获得更精确的死亡时间，其中以华中科技大学同济医学院教授刘良和他的团队为代表。《小鼠骨骼肌细胞核DNA降解与死亡时间的关系》《运用RNA降解规律构建数学模型推断死亡时间》《人体死后肝细胞DNA含量与死亡时间关系的研究》等研究成果都发表在杂志上。

但是，这些研究大多已停滞。业内人士告诉科技日报记者，这项研究后来进展不大，有些关键问题始终无法突破，个体差异和现实干扰因素等老问题无法解决，更重要的是成果始终无法从实验室走向应用。

因为实验室环境是稳定单一的，而真正发生的案件是非常复杂的，每一个细微的差别都会影响鉴定。何光龙认为，用人死后基因表达的变化来确定死亡时间的离真正应用还很远。

In the field of criminal investigation, the determination of the time of death is one of the most important clues of the case, and the related research around it has not ceased. But the reality is not as optimistic as we think. Experts say that the industry is still mostly using traditional methods, and the time of death is determined by gene expression. Although forensic experts have studied for many years, they still remain in laboratories, and there is still a long way to go for real applications.

There has been no perfect method

So far, the field of forensic science technology PMI, is mainly based on the body phenomenon, such as temperature, body, rigor mortis, stomach digestion and around the body, plant growth changes. Accurate inference of death time is a recognized problem in forensic science. At present, there is no "gold index" which is not affected by individual differences and postmortem changes, and can be applied to actual cases. He Guanglong, deputy director of the forensic pathology injury Technology Department of the Ministry of public security's physical evidence identification center, said.

From a professional point of view, the method of inferring the time of death based on the phenomenon of corpses is mostly related to statistics, and there are relevant formulas. However, what we are saying is that environmental factors such as temperature and humidity, physical and death causes of the dead will cause individual differences after death, which will affect the accuracy of the estimation of the time of death. For example, the body temperature changes to infer the early time of death in present case is widely used, but the change of the temperature change of the body temperature, clothing, status, environment and other factors. The corpse fat thin body temperature than the same environment decreased slowly; the body temperature warm indoor temperature. Cold outdoor cold slowly.  Therefore, the identification of the time of death by forensic medicine is a relatively rough time interval judgment.

Why "gene expression" is not reliable at present

Since about ten years ago, Chinese forensic science began to explore whether we could get more precise death time by monitoring the change of gene expression after death. Among them, Professor Liu Liang and his team from Tongji Medical College of Huazhong University of Science and Technology represented him. The relationship between the DNA degradation and the time of death in skeletal muscle of mice has been published in authoritative journals by using the mathematical model of RNA degradation rule to deduce the relationship between the time of death, the DNA content of postmortem hepatocytes and the time of death.

However, most of these studies have stagnated. Insiders told ScienceDaily Daily reporters that the research didn't progress very much, and some key problems could not be broken through. The old problems such as individual differences and realistic interference factors could not be solved, and more importantly, the results could never be applied from the laboratory to the application.

Because the laboratory environment is stable and single, and the real case is very complex, and every subtle difference will affect the identification. He Guanglong believes that the change in the expression of gene expression after death is far from the real application of the time of death.