立克次氏体3点免疫荧光玻片试剂盒

立克次氏体3点免疫荧光玻片试剂盒

Rickettsia 3-spot 12-well MIF Substrate Slide

广州健仑生物科技有限公司

主要用途：用于检测人血清中的立克次氏体 3 点抗体

产品规格：12 孔/张,10 张/盒

主要产品包括：包柔氏螺旋体菌、布鲁氏菌、贝纳特氏立克次体、土伦杆菌、钩端螺旋体、新型立克次体、恙虫病、立克次体、果氏巴贝西虫、马焦虫、牛焦虫、利什曼虫、新包虫、弓形虫、猫流感病毒、猫冠状病毒、猫疱疹病毒、犬瘟病毒、犬细小病毒等病原微生物的 IFA、MIF、ELISA试剂。

立克次氏体3点免疫荧光玻片试剂盒

我司还提供其它进口或国产试剂盒：登革热、疟疾、西尼罗河、立克次体、无形体、蜱虫、恙虫、利什曼原虫、RK39、汉坦病毒、深林脑炎、流感、A链球菌、合胞病毒、腮病毒、乙脑、寨卡、黄热病、基孔肯雅热、克锥虫病、违禁品滥用、肺炎球菌、军团菌、化妆品检测、食品安全检测等试剂盒以及日本生研细菌分型诊断血清、德国SiFin诊断血清、丹麦SSI诊断血清等产品。

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【公司名称】 广州健仑生物科技有限公司
【】    杨永汉 
【】 
【腾讯 】 2042552662
【公司地址】 广州清华科技园创新基地番禺石楼镇创启路63号二期2幢101-3室
【企业文化】

尽管科学界对脑卒中的认识和治疗有着显著进步，但开发新型和有效的治疗方式以对抗这种疾病仍然是一个主要的临床问题。由脑卒中引起的神经组织损伤是因为血流到大脑的中断造成的，并导致葡萄糖，氧和其他营养成分的缺乏。这会导致梗塞核心快速坏死，并形成缺血半影。这种半影可在亚急性期接受干预治疗。在众多的神经变性途径中，氧化应激已被证明可加剧中枢神经系统中次级细胞死亡。
DJ-1是一种多功能氧化还原敏感蛋白，与氧化应激的细胞死亡级联相关。DJ-1提供的神经保护形式可通过多种途径防止细胞死亡，zui重要的是通过降低线粒体氧化应激和PD聚集蛋白α-突触核蛋白分子陪伴(作用)，以及刺激抗凋亡和抗氧化基因的表达，促进促生存Akt通路从而阻止细胞凋亡信号调节激酶(ASK1)途径，并正调节雄激素受体依赖性转录。在细胞质和细胞核中常见的是，DJ-1可被分泌到病理状态下的血清中，还可以通过有丝分裂原刺激转位到各种哺乳动物细胞的线粒体中，特别令人感兴趣的是，氧化应激。
来自美国南佛罗里达大学医学院Cesar V. Borlongan教授所在团队讨论了其zui近发现的测试，DJ-1不仅可以作为氧化应激的细胞内保护的一种形式，也利用它从旁分泌和/或自分泌线索以完成相邻神经细胞之间的细胞外信号传导从而达到神经保护作用。相关研究内容发表在2014年8月第15期《中国神经再生研究(英文版)》杂志上。

Despite significant advances in the understanding and treatment of stroke in the scientific community, developing new and effective treatments to combat the disease remains a major clinical problem. Nerve tissue damage caused by stroke is caused by a breakdown of blood flow to the brain and results in a lack of glucose, oxygen and other nutrients. This can lead to rapid necrosis of the infarct core and the formation of ischemic penumbra. This penumbra can be sub-acute intervention in the treatment. Among numerous neurodegeneration pathways, oxidative stress has been shown to exacerbate secondary cell death in the central nervous system.
DJ-1 is a multifunctional redox-sensitive protein that is associated with a cascade of oxidative stress. The neuroprotective form provided by DJ-1 can prevent cell death through a variety of pathways, most importantly by reducing mitochondrial oxidative stress and companion (action) of the PD aggregin alpha-synuclein molecule as well as stimulating anti-apoptotic and anti- Oxidative gene expression promotes the pro-survival Akt pathway thus blocking the apoptotic signal-regulated kinase (ASK1) pathway and up-regulating androgen receptor-dependent transcription. It is common in the cytoplasm and nucleus that DJ-1 can be secreted into the serum under pathological conditions and can also be stimulated to translocate to the mitochondria of various mammalian cells by mitogens. Of particular interest is the oxidation of Stress.
The team from Professor Cesar V. Borlongan, University of South Florida School of Medicine, USA, discussed his recently discovered test that DJ-1 can be used not only as a form of intracellular protection of oxidative stress, but also from paracrine and / or Secretion of clues to complete the extracellular signal transduction between adjacent nerve cells to achieve neuroprotective effect. Relevant research is published in the 15th issue of "Chinese Journal of Nervous Regeneration Research (English Edition)" in August 2014.